Faculty Sponsor

George S. Mourad

Document Type

Presentation

Department/Program

Biology

University Affiliation

Indiana University-Purdue University Fort Wayne

IPFW Sigma Xi (Scientific Research Honor Society) Student Research Competition

Second Place

Abstract

Screening of an EMS-mutagenized population of Arabidopsis thaliana has revealed a fluoroorotic acid (FOA)-resistant mutant. Genetic analysis has shown that FOA resistance was due to a nuclear recessive gene, for1-1. Assays of key regulatory enzymes of the de novo synthesis and salvage of pyrimidines, and also uptake studies using radiolabelled purines and pyrimidines have revealed that for1-1/for1-1 plants were defective in the uptake of free uracil and uracil-like bases.

Presentation Date

4-9-2011

Included in

Biology Commons

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