Aminopropanol – Xylene to Chemically Purify Gd3N@C88 Metallofullerene
Inorganica Chimica Acta
The larger and less-studied metallic nitride fullerene, Gd3N@C88, is chemically isolated by manipulating its inertness to 3-aminopropanol in a xylene solvent system. An advantage of aminopropanol–xylene is the liquid phase of all species. This homogeneous nature mitigates sample loss that accompanies heterogeneous media, such as aminosilica. Respectful to green chemistry, our chemical purification approach eliminates chlorinated solvents. The inexpensive reagents require no preliminary synthesis prior to use. In stage one, fullerene and metallofullerene contaminants are easily transferred into a hydrophilic layer upon attaching water-soluble groups to the cage surface. In stage two, Gd3N@C88 is selectively precipitated with ZnCl2 and de-complexed to yield a sample of 84% purity. A single HPLC injection provides 99% Gd3N@C88.
Aminopropanol, Endohedral, Isolation, Metallofullerene, Non-chromatographic purification
Hannah R. Thompson, Hannah C. Masri, and Steven Stevenson (2017).
Aminopropanol – Xylene to Chemically Purify Gd3N@C88 Metallofullerene. Inorganica Chimica Acta.468, 177-182. Elsevier.