Faculty Sponsor

Robert J. Visalli

Document Type



Department of Biology

University Affiliation

Indiana University – Purdue University Fort Wayne

IPFW Sigma Xi (Scientific Research Honor Society) Student Research Competition



Known as the causative agent of genital herpes, HSV-2 infection affects half a billion people worldwide. When HSV-2 infects a host cell, the virus uses the host cell nucleic acid and protein synthesis machinery to replicate and assemble new viral particles. HSV-2, as well as the numerous other herpesviruses, have been shown to synthesize numerous immune modulation proteins. Some viral proteins work simultaneously to block interferon synthesis and its signaling effects.

Presentation Date


Included in

Biology Commons



To view the content in your browser, please download Adobe Reader or, alternately,
you may Download the file to your hard drive.

NOTE: The latest versions of Adobe Reader do not support viewing PDF files within Firefox on Mac OS and if you are using a modern (Intel) Mac, there is no official plugin for viewing PDF files within the browser window.