Faculty Sponsor
Robert J. Visalli
Document Type
Presentation
Department/Program
Department of Biology
University Affiliation
Indiana University – Purdue University Fort Wayne
IPFW Sigma Xi (Scientific Research Honor Society) Student Research Competition
Yes
Abstract
Known as the causative agent of genital herpes, HSV-2 infection affects half a billion people worldwide. When HSV-2 infects a host cell, the virus uses the host cell nucleic acid and protein synthesis machinery to replicate and assemble new viral particles. HSV-2, as well as the numerous other herpesviruses, have been shown to synthesize numerous immune modulation proteins. Some viral proteins work simultaneously to block interferon synthesis and its signaling effects.
Presentation Date
4-10-2010
Recommended Citation
Nnenna Ezeilo (2010).
The Herpes Simplex Virus Type-2 UL24 protein: A potential antagonist of the cellular interferon regulatory pathway.
https://opus.ipfw.edu/stu_symp2010/26