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Elliott Blumenthal; Daryoush Tahmassebi
The use of herbal remedies for the treatment of cancers has been increasing recently. Melanoma is the most dangerous type of skin cancer.. The primary aim of this study is to examine the anti-tumor effect of Origanum vulgare against B16 murine melanoma cells. The secondary aim is to observe the potential proliferative effect of O. vulgare on C57/BL6 spleen cells. The essential oil from the dried O. vulgare leaves was extracted via hydrodistillation. Previous studies have referenced different active compounds in the leaf extract of O. vulgare. For this particular study, a carvacrol solution was utilized to serve as a control solution in reference to the leaf extract of O. vulgare. Moreover, this helped standardize the effectiveness of the essential oil itself. Specific dilutions of the leaf extract were able to decrease melanoma cell counts as well as increase spleen cell counts. In conclusion, this study demonstrates that the essential oil of the O. vulgare plant has the potential to serve as an effective component for inducing melanoma cell growth inhibition as well as spleen cell proliferation.
Biology | Chemistry
Hamilton, Connor, "The Effects of Oregano (Origanum Vulgare) Leaf Extracts on Tumor Cell Growth and Immune Response" (2018). 2018 IPFW Student Research and Creative Endeavor Symposium. 36.